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What's your position and where are you working? For the past 5 years I have worked as a lecturer in Biological Chemistry in the section of Biomolecular Medicine at Imperial College London. Where have you been working before? Before this, I post-doc�ed at Cambridge; before that, UC Davis; and before that, for my first post-doc, at Imperial College again. Briefly describe your research. I am interested in metabolism in invertebrate and microbial species, and how this is involved in several different biological questions. Some of the projects I currently work on include microbial virulence and pathogenesis; how metabolism is affected by problems with recombinant protein folding in the bioprocessing yeast Pichia pastoris; and using earthworms as biomonitors of environmental pollution. What do you use NMR for? Together with mass spectrometry, I use NMR for metabolite profiling, as part of the technology for metabolomic studies. Although it�s generally less sensitive than mass spec, NMR...

A measure of the computing power available today with a desktop computer is the possibility of processing huge spectra in real time. For example: is it possible to correct the phase of a 3-D matrix interactively, in real time? The answer is: yes and you don't even have to employ more than a single core nor to buy an high-end graphic card. When I mean interactive processing I mean that: - you see a graphic representation of the matrix at each processing stage. - you can play with it, for example change a parameter just to see the effect it has on the matrix. It is always necessary to know and understand the mathematical rules that govern NMR processing. The more you know them the more you enjoy their visual representations. The more you play with the graphics, the more you understand the maths behind. The two things go together. You can find a self-teaching course on basic 3-D processing on the iNMR web site. There is no theory, only a lot of examples and a good measure of practica...