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Showing posts from June, 2009

Daniel J. Weix

Q. What's your position and where are you working? A. Assistant Professor, University of Rochester. Q. Briefly describe your research. A. Synthetic organic methodology, especially catalysis. Q. What do you use NMR for? A. Assaying purity of synthesized materials and identification of products (both organic and inorganic). Q. Which NMR software are you using? A. We use iNMR, latest version. Q. Which other NMR software have you used in the past? A. I have used MestreC, Bruker XWIN-PLOT, NUTS, MacNUTS (new version), and MestreNOVA. Q. How do you rate iNMR? A. I like iNMR better than all of the other software that I have used. The workflow is good and I'm already almost as fast as I was under NUTS (the fastest software of those mentioned above). It seems superior to MestreNOVA, with better keyboard shortcuts (MestreNOVA involved a lot of clicking) and a better user interface. New features are discoverable vs. having to dig into the manual. Importantly, my students l...

Bernhard Jaun

Q. What's your position and where are you working? A. Professor in Organic Chemistry at ETH Zurich (Swiss Federal Institute of Technology). Head of the NMR labs. Q. Where have you been working before? A. Columbia University New York, then ETH Zurich for the last 29 years. Q. Briefly describe your research. A. Physical organic chemistry, in particular its application to biological questions. Q. What do you use NMR for? A. I am the head of NMR operations in an institute with more than 200 scientists. Most of them use NMR. The applications go from 3D solution structures of biopolymers to physical organic applications of NMR (such as host guest complexation, dynamic processes, thermodynamics and kinetics) to structure elucidation of novel natural compounds and (for the majority) characterization of synthetic intermediates. Q. Which NMR software are you using now? A. Topspin, VNMR, Mnova, iNMR, plus specialized software for 3D solution structure calculation such as XPLOR, SPARKY, ...

Antonio Randazzo

Q. What's your position and where are you working? A. I am an Associate Professor at the Faculty of Pharmacy - University of Naples "Federico II"- Italy Q. Where have you been working before? A. I have worked also at The Scripps Research Institute (San Diego - California - USA) and at the Vanderbilt University (Nashville - Tennessee - USA) Q. Briefly describe your research. A. I have worked in the field of Bioactive Natural Product. I was in charge of the isolation and structural elucidation of new secondary metabolites from marine organisms. The characterization of the new compounds has been accomplished mainly by NMR. Then I moved to the structural study of protein by NMR. Currently I study unusual structures of DNA. In particular I study the structure of modified DNA quadruplex structures....always by means of NMR. I had the occasion to use NMR also in the field of food science. Q. Which NMR software are you using now? A. Currently I am using iNMR on two different ...

Arthur Roberts

Q. Please introduce yourself to the readers of the NMR software blog. A. I am a project scientist at the School of Pharmacy at the University of California San Diego (UCSD). I was hired to bring some novel NMR technology that I developed at the University of Washington to UCSD. I worked as a postdoctoral fellow at the Department of Medicinal Chemistry at the University of Washington and at Washington State University. I started my career as an EPR spectroscopist, where we built instruments. I have been doing NMR, since 2003. Currently I study the process of drug metabolism, which happens to be the main road block for drug development. We hope that our research will lead to drugs of higher efficacy and fewer side effects. We are developing NMR technology that will allow us to rapidly determine drug bound structures and will speed drug development. We have developed a variety of NMR pulse programs for this purpose. We do Paramagnetic protein NMR. We also do NMR simulations and writ...

Stefano Antoniutti

Q. Please introduce yourself to the readers of the NMR software blog. A. My position is Associate Professor in General and Inorganic Chemistry since year 2000 at the Dept. of Chemistry, Universit� di Venezia Ca' Foscari, Italy. I am responsible for Dept. NMR instrumentation and services since Year 1992. I entered the Department in 1983 as a researcher. Since 1983 I have my name in more than 80 scientific papers on ISI classified journals in the field. My research area is in the field of Inorganic and Organometallic transition metal complexes. The research group I belong to is involved mainly in synthesis and characterization of new complexes. NMR is the main way of characterization of our new compounds. I began using permanent magnet-pen plotter-1H CW instruments in the early '80s; moved to monodimensional FT NMR in the '80s; today use of multidimensional, multinuclear NMR (1H, 31P, 13C, 15N, 119Sn etc) is my daily routine. Since 1995 in our Dept. we separated acquisit...