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Showing posts from July, 2010

The Barrier

In the last two years NMR software has kept evolving slowly, but the world around it is changing more rapidly. From a technical point of view nothing important happened; while from a commercial point of view we are in the middle of a revolution. Prices have dropped down considerably. The false categories, the so-called "professional", "industry-standard" programs on a side and "low-budget", "alternative" programs on the other side, have disappeared. The companies that were selling the products in the first category have realized that the true values were actually reversed and adjusted the prices accordingly. Consider TopSpin, for example. I remember its original price was in the range � 4000-5000. At the beginning of the month, I have visited an industrial lab where they had recently purchased a license for off-line processing. They told me they had paid � 3000 for TopSpin. They had also considered a solution by ACDlabs, but after receiving a quo...

Universal Hole

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Earlier in this week I cited a paper by Kobzar and Luy. It contains the statement: The coupling extraction procedure is not yet implemented in any available software. that confirms and enforces what I have always being saying: Any NMR program contains some hole and by the time it's filled another hole appears. What they have found is a kind of super-hole that is common to every program. My first thought would normally be: "If nobody cares, why should I?", but this time I was intrigued by a figure just above the cited statement. That figure resembles a picture of mine I published here a few months ago. Despite the apparent similarity, however, the two methods have little in common. Driven by curiosity, I looked on the web for anything more recent on the same subject and found this page that describes the very same "long range J" procedure. Does it mean that somebody has already filled the hole? I have contacted the PR man at nucleomatica and he explained that t...